Discussion
AMBIO is working for 10 years, now (AMBIO is short for Advances Medical BIOimaging core facility of the @ChariteBerlin ).
Today we have a symposium with lots of talks, but also expert tables, device demos and an microscopy image competition.Brace for some talk summaries and probably very pretty flourescence microscopy images. #AMBIO10years #AMBIO
edit info: corrected the language and made the alt text of the image more detailed. #alttext
After some nice introduction speaches by Britta Eickholt, the dean of faculty, and the Nikon General Manager, our #AMBIO Head Jan Schmoranzer gives an overview over the last 10 years of core facility work.
Now, Ralf Jungmann from the MPI Biochemistry in Munich is talking about their approach of sub nanometer flourescence microscopy with DNA-Paint and RESI with many biological applications. #AMBIO10years
And here the image of Ralf Jungmanns last slide and a link to his Lab: https://www.biochem.mpg.de/jungmann/
Next is Marina Mikhaylova from HU Berlin, talking about Imaging in Neuroscience. #AMBIO10years
Closing the morning session is Kai Murk, from the AG Eickholt, here at Charitė. He is talking about Astrocytes, and mainly about astrocytes in tissue and reaction to injury and wounds, with some examples also from live cell imaging. #AMBIO10years
After a short coffee break, Jost Enninga from Institue Pasteur Paris is talking about intracellular lifestyles of pathogenes, and how he and his group is observing this at the microscope. #AMBIO10years
Jost presented a workflow and a toolbox to analyse data for everyone to use. This was all to quick, I could not include videos, but the capabilities are very impressive, judging from the animations/zoom. #AMBIO10years
And one image more from Jost: How shigella bacteria poke holes in cell membranes with their "bacterial needles" #AMBIO10years
The next talk is by Nadja Hümpfer from the @ewerslab at @fubcp .
She did a lot of imaging at #AMBIO at our light-sheet microscope, to look at living cells for a long time, without photodamage. #AMBIO10years
Nadja could enter "the dark zone", the mid body, by expansion microscopy. Here is a nice slide with an overview of the principles of the technique. #AMBIO10years
Now Oliver Rocks from @ChariteBerlin is talking about... giant membrane rods, they found, did not what they were, found out that the effect is temperature dependent and started a project.
It is a fascinating journey he is taking us on. #AMBIO10years
Niklas Semhaas from Nikon is giving an overview of hoa Nikon started and then how #AMBIO started. We are also an "Nikon center of excellency", that helps a lot to run our core facility at such high microscope booking numbers we see here at AMBIO. #AMBIO10years
After the lunch break, Jan Schmoranzer, the head of #AMBIO, tells us what is comming for the next #AMBIO10years , starting with new Systems and GPU Server next year and the long term plans further ahead.
Now Bettina Weigelin from Uni Tübingen is talking about multiscale microscopy to understand systematic immune response against metastatic cancer.
T-Cells can kill Tumor cells, but it is a stochastic process and needs more than one T-Cell, so they are not checking if they made the kill. Probably a saftey featur, but a problem against cancer. #AMBIO10years
Side note: I am tooting live from the symposium and I am chair of every other session. Alt text is rudimentary at the moment, i will go back to it and improve later, sorry. #alttext
Bettina Weigelin continues her talk, with some results about cancer treatment, higher tempreatures and some learnings from that. This is pre- clinical data. #AMBIO10years
And now she introduces us to their tissue clearing approach to study a lot bigger pierces of tissue. #AMBIO10years
And her summay as a photo, fascinating talk. #AMBIO10years
Friedrich Johenning from the @ChariteBerlin is talking now about feeding behavior, and als analysing the sensing systemstics within the body and on a cellular level. #AMBIO10years
Now Felix Haymann from the @ChariteBerlin at Virchow Klinikum is talking about multiphoton imaging, intravital as well as flourescence life-time imaging and applying those techniques to investigating liver diseases. #AMBIO10years
Next talk is by Dragomir Milovanovic from @ChariteBerlin and @dzne about imaging the interfaces between condensates and membrane-bound organelles. #AMBIO10years
The last talk by Susanne Wegmann of @ChariteBerlin and @dzne about her Favorit: Tau Protein (actually celebrating 20 years of discovery this year) and the fuzzy coat, containg several Tau Proteins, featuring a lot of microscopy images taken at #AMBIO. #AMBIO10years
After this, the winners of the microscopy image competition will be announced, and we have some handmade prizes for them. #AMBIO10years
